slipped upper femoral epiphysis

definition

·      disorder of proximal femoral epiphysis in puberty with slip through physis

epidemiology

·      incidence 2 per 100 000

·      occurs in 2 yr period around puberty

·      11-13 in girls

·      13-15 in boys

·      av. 18 months before closure of epiphysis

·      more common in

·      boys (3:1)

·      blacks (2:1)

·      left hip

·      most patients have

·      obesity

·      delayed skeletal maturation

·      delayed sexual maturation

·      associated with

·      hypothyroidism

·      pituitary dysfunction

·      advanced renal disease

·      bilateral in 50% (25-75%)

aetiology
Endocrine

·      may be imbalance between sex hormones and growth hormone

·      growth hormone shown to weaken growth plate

·      sex hormones shown to strengthen growth plate

·      slip in growing child with deficient sex hormones

·      supported by many facts

·      occurs during period of hormonal change

·      sometimes associated with abnormality in hormonal function

·      patient are sexually immature

Trauma

·      slip due to forces of

·      gravity

·      weight-bearing

·      muscle activity

·      probably physiological forces acting on pathologically weak physis rather than pathological forces acting on normal physis

pathology
Histology

·      weakness of perichondrial ring

·      slip occurs through hypertrophic zone

·      near junction with proliferative zone

·      cf. Salter Harris fractures which occur near junction with zone of provisional calcification

·      physis shows disruption

·      thickening

·      distortion of columnar arrangement

·      synovium becomes oedematous and vascular

Anatomy

·      head remains in acetabulum

·      attached by ligamentum teres

·      head slips posteriorly on neck

·      neck externally rotates

·      new bone laid down on back of femoral neck

Natural history

·      slip usually proceeds slowly

·      symptoms usually start some time after slip

·      progressive slipping usually occurs

·      remodelling of neck occurs simultaneously

·      remodelling usually significantly corrects deformity

·      esp. if triradiate cartilage still open

·      shown to lead to premature osteoarthritis

·      characteristic pistol-grip deformity of femoral neck 2o to SUFE common in arthritic hips

·      severity of OA related to severity of slip

·      treatment to prevent further slip can decrease OA

·      poor results accelerated by

·      chondrolysis

·      avascular necrosis

clinical
History

·      usually insidious onset of pain

·      groin and thigh

·      knee (may be only site)

·      may sometimes be sudden pain afer minor trauma

Examination

·      externally rotated leg

·      antalgic gait

·      abductor lurch

·      positive Trendelenburg sign

·      may be shortening

·      wasting of thigh in chronic slip

·      decreased ROM

·      esp. IR in flexion

·      leg usually externally rotates when flexed

·      associated synovitis causes pain and mild restriction in other ranges

Radiology
Plain x-rays

·      AP and lateral (true or frog-leg)

·      if severe, slip easily visualised

·      if mild, subtle signs on AP

·      reduced epiphyseal height

·      widening of physis

·      blurring of metaphysis

·      Trethowan’s line (line along superior neck) does not intersect any of epiphysis

·      femoral head appears to be in varus

·      Shenton’s line may be broken

classification
Presentation

·      classified on duration of symptoms

Acute

·      symptoms < 3 wks

·      new slip on x-ray

Chronic

·      symptoms > 3 wks

Acute on chronic

·      symptoms < 3 wks

·      old slip on x-ray

Degree

·      classified on degree of slip on x-ray

Grade 1

·      slip of < 1/3 of width of physis

Grade 2

·      slip of 1/3 to 1/2 of width of physis

Grade 3

·      slip of > 1/2 of width of physis

treatment
Goals

·      prevent further slip

·      promote premature fusion of epiphysis

·      avoid iatrogenic complications

·      chondrolysis

·      avascular necrosis

Principles

Primary treatment

·      to prevent further slip

Pinning in situ

·      most common technique

·      associated with

·      chondrolysis

·      avascular necrosis

Epiphyseodesis

·      open procedure with bone graft

·      advocated to avoid complications of pinning

·      more difficult procedure

·      limited experience

Secondary treatment

·      to reduce slip that is present

Manipulation

·      most often used for acute SUFE

·      successful in only 50%

·      may predispose to avascular necrosis

·      not advocated

Osteotomy

·      performed to

·      prevent onset of OA

·      alter arch of motion

Tertiary treatment

·      salvage procedures

·      for patients with

·      avascular necrosis

·      chondrolysis

Osteotomy

·      may be indicated for limited segmental AVN

Arthroplasty

·      not usually advocated because of poor longevity in young patients

·      may be indicated in bilateral disease

·      esp. on one side

Arthrodesis

·      procedure of choice for unilateral hip joint desruction

Pinning in situ

Principles

·      pin must not penetrate joint

·      two radiographic images at right angles

·      pin must be in central axis of femoral head

·      both on AP and lateral

·      entry point in anterior neck

·      because head displaced posteriorly

·      single cannulated screw

·      increased complication risk with multiple screws

·      must be strong enough

·      cannulation allows percutaneous techniqe

Technique

·      image intensifier

·      traction table

·      percutaneous approach

·      starting point on anterior neck

·      guide wire positioned and checked

·      6.5 mm cannulated screw inserted

·      advanced to no more than 5 mm of subchondral surface

·      screw checked in two planes with rotation technique

·      arthrogram performed through screw

Postoperative

·      mobilise with crutches next day

·      home when safe

·      protected wt bearing for 6 weeks

·      followup with x-ray at 4 month intervals until physis closed

·      usually closed with 12 months

Removal

·      advocated because of increased likelihood of need for THR in future

·      may be difficult to remove because of bone overgrowth

·      probably can be left in

·      if removal desired, should be done

·      early

·      with II, guide wire and semi-percutaneous technique

Complications

General

·      in form of

·      chondrolysis

·      avascular necrosis

·      occurs in 20%

·      related to

·      severity of slip

·      number of pins used

·      persistent pin penetration

Pin-related

·      loss of fixation

·      back out

·      breakage

·      subtrochanteric fracture

·      infection

Prophylactic

·      advocated because of high incidence of bilaterality

·      may cause complications

·      not usually indicated

·      may have place in patients with

·      unreliable carers

·      geographic isolation

·      metabolic or endocrine cause

Osteotomy

Indications

·      prophylactic

·      correction of deformity may decrease incidence of OA

·      no clear evidence

·      remodelling usually significantly corrects deformity

·      probably not indicated

·      symptomatic alteration of arch of motion

·      loss of internal rotation, flexion and abduction may be severe

·      disability may be functional rather than just cosmetic

·      should wait at least 12 months as significant improvement likely

·      symptomatic collapse of avascular segment

·      valgus osteotomy may shift more normal articular cartilage to superior weight-bearing area

·      most cases do not remain symptomatic

Principles

·      safest procedure is away from blood supply of femoral head

·      needs to offer sufficient correction

Technique

·      Southwick intertrochanteric osteotomy

·      wedge of bone removed from anterolateral proximal femur near lesser trochanter

·      wedge closed and distal fragment internally rotated

·      head brought into more normal relationship with acetabulum and femoral shaft

·      secondary deformity produced in intertrochanteric region

Complications

·      avascular necrosis

·      significantly decreased with intertrochanteric cf. head or neck osteotomy

·      chondrolysis

·      reason for increased incidence unclear

Protocol

·      pin all in situ on presentation

·      delayed intertrochanteric osteotomy with significant symptomatic deformity

COmplications
Chondrolysis

Definition

·      destruction of articular cartilage with secondary loss of joint space and stiffness

Aetiology

·      most cases occur after treatment of SUFE

·      may also occur with

·      prolonged immobilisation

·      trauma

·      severe burns

·      idiopathic

SUFE-associated

·      incidence of 20%

·      increased incidence with

·      severe slip

·      blacks and girls

·      persistent pin penetration (50%)

Pathogenesis

·      theories are

·      lack of production of synovial fluid

·      immune process

Pathology

·      first stage is synovitis

·      next stage is cartilage destruction

·      final stage is synovial and capsular fibrosis and exposed articular bone covered with granulation tissue

Clinical

·      pain

·      decreased ROM

·      contracture

·      flexion and adduction contracture in SUFE

·      abduction contracture in idiopathic

Radiology

·      loss of joint space

·      osteoporosis

·      premature closeure of physes

Differential diagnosis

·      septic arthritis

Natural history

·      varies from

·      transient pain and stiffness with joint narrowing

·      fulminating course with ankylosis in few months

Treatment

Acute

·      NSAIDs

·      traction

·      CPM

Salvage

·      arthrodesis

Avascular necrosis

·      does not occur in untreated SUFE

·      occurs with treatment

·      manipulation

·      pinning

·      osteotomy

·      occurs most frequently after acute SUFE

·      incidence of 15%

·      may be due to

·      vascular interruption with forced manipulation

·      vascular disruption by screw

·      may lead to chondrolysis

·      necrosis may lead to collapse with subsequent pin penetration

Degenerative joint disease

·      related to

·      severity of slip

·      associated chondrolysis or avascular necrosis